Index: src/Deltares.DSoilModel.Forms/DSoilModelPlugin.cs
===================================================================
diff -u -r405 -r417
--- src/Deltares.DSoilModel.Forms/DSoilModelPlugin.cs	(.../DSoilModelPlugin.cs)	(revision 405)
+++ src/Deltares.DSoilModel.Forms/DSoilModelPlugin.cs	(.../DSoilModelPlugin.cs)	(revision 417)
@@ -971,6 +971,7 @@
             };
             mainForm.RegisterTableControl(typeof(Soil), materialsTable, "Materials");
             BindSupport.Bind(projectPanel, materialsTable, typeof(DSoilModelProject), "Soils.Soils");
+            materialsTable.CanDelete += CanDelete;
 
             var cptsTable = new GridViewControl
             {
@@ -1077,6 +1078,33 @@
             mainForm.DynamicOutputControl.LogMessagesGridViewControl.ShowToolbar = true;
         }
 
+        private void LogErrorCannotDelete(IName objToDelete, IName objUses)
+        {
+            var formattedErrorStr = LocalizationManager.GetTranslatedText(this, "CannotDeleteObjectThatInUse");
+            // Cannot delete {0} [{1}] because it's used in {2} [{3}]"
+            var msg = string.Format(formattedErrorStr, objToDelete.Name, objToDelete.GetType().Name, objUses.Name, objUses.GetType().Name);
+            LogManager.Add(new LogMessage(LogMessageType.Error, objUses, msg));
+        }
+
+        private bool CanDelete(object o)
+        {
+            var result = true;
+            var soil = o as Soil;
+            if (soil != null)
+            {
+                foreach (var sp1d in project.SoilProfiles1D)
+                {
+                    if (sp1d.Layers.Any(l => l.Soil == o))
+                    {
+                        LogErrorCannotDelete(soil, sp1d);
+                        result = false;
+                    }
+                }
+            }
+
+            return result;
+        }
+
         private void RemoveBarButtonItem(GridViewControl gridViewTable, string buttonName)
         {
             var manager = gridViewTable.Toolbar.Manager;
Index: src/Deltares.DSoilModel.Forms/Translations.xml
===================================================================
diff -u -r342 -r417
--- src/Deltares.DSoilModel.Forms/Translations.xml	(.../Translations.xml)	(revision 342)
+++ src/Deltares.DSoilModel.Forms/Translations.xml	(.../Translations.xml)	(revision 417)
@@ -92,4 +92,6 @@
   <Translation ID="ExecuteClearSoilProfile2DCommandUserConfirm" en-US="Do you want to clear 2D profile?" nl-NL="Wilt u 2D profiel leegmaken?" />
   <Translation ID="SoilProfile1DLookup2DControl" en-US="1D Profile" nl-NL="1D Profiel" />
   <Translation ID="CombinerError" en-US="2D Combiner Error" nl-NL="2D Combinatie Fout" />
+  
+  <Translation ID="CannotDeleteObjectThatInUse" en-US="Cannot delete {0} [{1}] because it's used in {2} [{3}]" nl-NL="NL::Cannot delete {0} [{1}] because it's used in {2} [{3}]" />
 </Translations>